Bone 42(3):476–482CrossRefPubMed 24. Hodges SJ, Akesson K, Vergnaud P, Obrant K, Delmas PD (1993) Circulating levels of vitamins K1 and K2 decreased in elderly women with hip fracture. J Bone Miner Res
8(10):1241–1245PubMedCrossRef 25. Kanai T, Takagi T, Masuhiro K, Nakamura M, Iwata M, Saji F (1997) Serum vitamin K level and bone mineral density in post-menopausal women. Int J Gynaecol Obstet 56(1):25–30CrossRefPubMed 26. Luukinen H, Kakonen SM, Pettersson K, Koski K, Laippala P, Lovgren T, Kivela SL, Vaananen HK (2000) Strong prediction of fractures among older adults by the ratio of carboxylated to total serum osteocalcin. J Bone Miner Res 15(12):2473–2478CrossRefPubMed 27. Vergnaud P, Garnero P, Meunier PJ, Breart G, TGF-beta inhibitor Kamihagi K, Delmas PD (1997) Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: the EPIDOS Study. J Clin Endocrinol Ilomastat solubility dmso Metab 82(3):719–724CrossRefPubMed 28. Booth SL, Tucker KL, Chen H, Hannan MT, Gagnon DR, Cupples LA, Wilson PW, Ordovas J, Schaefer EJ, wson-Hughes
B, Kiel DP (2000) Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr 71(5):1201–1208PubMed 29. Feskanich D, Weber P, Willett WC, Rockett H, Booth SL, Colditz GA (1999) Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr this website 69(1):74–79PubMed 30. Hirao M, Hashimoto J, Ando W, Ono T, Yoshikawa H (2008) Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with vitamin K2 in postmenopausal women. J Bone Miner Metab 26(3):260–264CrossRefPubMed 31. Akiyama Y, Hara K, Ohkawa I, Tajima T (1993) Effects of menatetrenone on bone loss induced by ovariectomy
in rats. Jpn J Pharmacol 62(2):145–153CrossRefPubMed 32. Mawatari T, Miura H, Higaki H, Moro-Oka T, Kurata K, Murakami T, Iwamoto Y (2000) Effect of vitamin K2 on three-dimensional trabecular microarchitecture in ovariectomized rats. J Bone Miner Res 15(9):1810–1817CrossRefPubMed check details 33. Shiraishi A, Higashi S, Masaki T, Saito M, Ito M, Ikeda S, Nakamura T (2002) A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis. Calcif Tissue Int 71(1):69–79CrossRefPubMed 34. Binkley N, Krueger D, Engelke J, Suttie J (2007) Vitamin K deficiency from long-term warfarin anticoagulation does not alter skeletal status in male rhesus monkeys. J Bone Miner Res 22(5):695–700CrossRefPubMed 35. Price PA (1985) Vitamin K-dependent formation of bone Gla protein (osteocalcin) and its function. Vitam Horm 42:65–108CrossRefPubMed 36. Koshihara Y, Hoshi K, Ishibashi H, Shiraki M (1996) Vitamin K2 promotes 1alpha, 25(OH) 2 vitamin D3-induced mineralization in human periosteal osteoblasts. Calcif Tissue Int 59(6):466–473PubMed 37.