Cell 124:263–266PubMedCrossRef

72. Tan TT, Coussens LM (2007) Humoral immunity, inflammation and cancer. Curr Opin Immunol 19:209–216PubMedCrossRef 73. Witz IP (2008) Yin-yang activities and vicious cycles in the tumor microenvironment. Cancer Res 68:9–13PubMedCrossRef 74. Mantovani A, Bottazzi B, Colotta F et al (1992) The origin and function of tumor-associated AUY-922 datasheet macrophages. Immunol Today 13:265–270PubMedCrossRef 75. Brigati C, Noonan DM, Albini A et al (2002) Tumors and inflammatory infiltrates: Friends or foes? Clin Exp Metastasis 19:247–258PubMedCrossRef 76. Dirkx AE, Oude Egbrink MG, Wagstaff J et al (2006) Monocyte/macrophage infiltration in tumors: Modulators of angiogenesis. J Leukoc Biol 80:1183–1196PubMedCrossRef 77. Lamagna C, Aurrand-Lions M, Imhof BA (2006)

Dual role of macrophages in tumor growth and angiogenesis. J Leukoc Biol 80:705–713PubMedCrossRef 78. Talmadge JE, Donkor M, Scholar E (2007) Inflammatory cell selleck infiltration of tumors: Jekyll or Hyde. Cancer Metastasis Rev 26:373–400PubMedCrossRef 79. Whitworth PW, Pak CC, Esgro J et al (1990) Macrophages and cancer. Cancer Metastasis Rev 8:319–351PubMedCrossRef 80. Pak CC, Fidler IJ (1991) Molecular mechanisms for activated macrophage recognition of tumor cells. Semin Cancer Biol 2:189–195PubMed 81. Lin EY, Pollard JW (2004) Role of infiltrated leucocytes in tumour growth and spread. Br J Cancer 90:2053–2058PubMedCrossRef PIK3C2G 82. Pollard JW (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4:71–78PubMedCrossRef 83. Mantovani A, Schioppa T, Porta C et al (2006) Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev 25:315–322PubMedCrossRef 84. Pawelek J, Chakraborty A, Lazova R et al (2006) Co-opting macrophage

traits in cancer progression: A consequence of tumor cell fusion? Contrib Microbiol 13:138–155PubMedCrossRef 85. Allavena P, Sica A, Solinas G et al (2008) The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages. Crit Rev Oncol Hematol 66:1–9PubMedCrossRef 86. Gazzaniga S, Bravo AI, Guglielmotti A et al (2007) Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J Invest Dermatol 127:2031–2041PubMedCrossRef 87. Schwantke N, Le Bouffant F, Dorée M et al (1985) Protein kinase C: properties and possible role in cellular division and differentiation. Biochimie 67:1103–1110PubMedCrossRef 88. Cohen I, Van der Kloot W (1985) Calcium and transmitter release. Int Rev Neurobiol 27:299–336PubMedCrossRef 89. Stryer L, Bourne HR (1986) G proteins: a family of signal transducers. Annu Rev Cell Biol 2:391–419PubMedCrossRef 90. Bregman MD, Sipes NJ (1986) Transformation-related growth factors and their receptors. Int J Cell Cloning 4:224–236PubMedCrossRef 91.