Conclusions: The KineSpring System demonstrated safety in a simulated use model for periods of up to fifty-two weeks. Screws result in stable implant fixation and TPS-HA coating allows for early and long-lasting cortical bone PP2 apposition and integration.”
“Radiation damage induced by high-energy (200 keV) electron irradiation in zircon has been studied thoroughly using imaging, diffraction, and electron energy-loss spectroscopy techniques in transmission electron microscopy. Both structural and compositional changes during the

damage were measured using the above techniques in real time. It was found that the damage was mainly caused by the preferential sputtering of O. The loss of O occurred initially within small sporadic find more regions with dimension of several nanometers, resulting in the direct transformation of zircon into ZrxSiy. These isolated patches gradually connect each other and eventually cover the whole area of the electron beam. These differ from the previous observations either in the self-irradiated natural and synthetic zircon or in ion-beam irradiated thin zircon specimen. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3151704]“
“Background and aims: To determine whether

the relation between waist circumference (WC) and cardiometabotic risk markers is attenuated with advancing age.

Methods and results: The study population consisted of 5222 adults from the 1999 to 2004 U.S. National Health and Nutrition Examination Survey, a nationally

representative cross-sectional study. Study variables were assessed in a clinical exam. Subjects were grouped into low, moderate, and high sex-specific WC tertiles. The cardiometabotic risk markers examined consisted of insulin resistance (HOMA method), Metabolism inhibitor high C-reactive protein, hypertension, and high LDL-cholesterol. Logistic regression was used to determine and compare the association between WC categories with high-risk cardiometabolic risk marker values within young (20-39 years), middle-aged (40-59 years), and older (60+ year) adults. With few exceptions, within each of the three age categories, individuals with a moderate and high WC were significantly more likely to have elevated cardiometabotic risk markers than individuals with a tow WC. There was a significant interaction between age and WC indicating that the relation between WC with insulin resistance, high CRIP, and hypertension was attenuated in older adults. For example, the odds ratio for hypertension in those with a high relative to tow WC was 11.07 (95% CI: 6.13-20.00) in young adults, 3.67 (2.47-5.46) in middle-aged adults, and 2.68 (2.00-3.59) in older adults. Similar observations were made for BMI to those reported for WC.

Conclusions: A high WC was associated with elevated cardiometabotic risk markers irrespective of age. However, the association between WC and cardiometabotic risk markers was greatly attenuated with advancing age. (C) 2008 Elsevier B.V. All rights reserved.