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during laparoscopic nephrectomy. J Urol 2001, 165:1203–1204.PubMedCrossRef Competing interest All Authors does not have any financial relationship with any organization. No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. All authors have the full control of all primary data and that they agree to allow the journal to review their data if requested. All authors contributed to the realization of this manuscript. The authors declare that they have no competing interests. Authors’ contributions All of the authors were involved in the preparation of this manuscript.MS write the manuscript coordinated the team, and helped in literature research. HM was an assistant surgeon and made substantial contributions to conception and design. YPL performed the operation and edited the final version of the manuscript. All authors read and approved the final manuscript.”
“Introduction Intra-abdominal infections check details (IAIs) TSA HDAC clinical trial include a wide spectrum of pathological conditions, ranging from uncomplicated appendicitis to fecal peritonitis [1]. From a clinical perspective, IAIs are classified

in two major categories: complicated and uncomplicated. In uncomplicated IAIs, the infectious process only involves a single organ SPTLC1 and does not spread to the peritoneum. Patients with such infections can be managed with either surgical resection or antibiotics. When the focus of infection is treated effectively by surgical excision, 24-hour perioperative prophylaxis

is typically sufficient. Patients with less severe intra-abdominal infections, including acute diverticulitis and certain forms of acute appendicitis, may be treated non-operatively. In complicated IAIs, the infectious process extends beyond a singularly affected organ, and causes either localized peritonitis or diffuse peritonitis. The treatment of patients with complicated intra-abdominal infections involves both source control and antibiotic therapy. Intra-abdominal infections are further classified in two groups: community-acquired intra-abdominal infections (CA-IAIs) and healthcare-associated intra-abdominal infections (HA-IAIs). CA-IAIs are acquired directly in the community while HA-IAIs develop in hospitalized patients or residents of long-term healthcare facilities. HA-IAIs are associated with higher rates of mortality due to the patients’ poorer underlying health and an increased likelihood of infection by multi-drug resistant microorganisms. Source control encompasses all measures undertaken to eliminate the source of infection and to control ongoing contamination.