The influence of a cosolvent (methanol) at various concentrations was studied regarding physical properties, morphology, and in vitro release profiles of the drugs from the PDLLA nanofibers. Swelling selleck chemical tests in a physiological

buffer solution were performed to determine the extent an rate of swelling of the fiber mats. The results showed that for both drugs electrospun fiber diameters decreased with increasing amounts of cosolvent, whereas water contact angles and drug-loading efficiency increased. However, similar in chemical structure, the two drugs exhibited considerably different release mechanisms. The results indicated that the concentration of methanol changed the release profiles mainly based on the morphology of the resultant nanofibers and the polymer/drug/solvent interaction during the electrospinning and drug release process. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 115:1-8,2010″
“A full structural investigation was carried out on novel lead-free piezoelectric solid solutions of xBiScO(3)-(1-x)BaTiO3 (BS-BT) between x = 0.0 Autophagy Compound Library cost and 0.35 utilizing x-ray and neutron powder diffraction. This particular system demonstrated an extended tetragonal-pseudocubic phase boundary at room temperature in the region 0.05 <= x <=

0.20. Rietveld refinements were performed on the neutron powder diffraction data to obtain detailed crystallographic information across the phase diagram of this binary system. The best model to describe the phase boundary was found to be a mixture of tetragonal www.sellecn.cn/products/pci-34051.html (P4mm) and strongly pseudocubic rhombohedral (R3m) phases. Non-ambient x-ray diffraction patterns were collected in the temperature range of -253 to 325 degrees

C to elucidate the effect of incorporation of BiScO3 on the temperature-dependent structural phase transitions of BaTiO3. Interestingly, the BS-BT system for x >= 0.05 demonstrated only one structural phase transition, which is the ferroelectric to paraelectric phase transition, suppressing the other two low temperature phase transitions. High-temperature dielectric properties were also studied in order to examine the physical properties of the ceramics. (c) 2010 American Institute of Physics. [doi:10.1063/1.3309064]“
“Dendritic macromolecules containing several types of functional groups were successfully synthesized through divergent method. Poly(ethylene glycol) was functionalized using cyanuric chloride and it was reacted. with p-toluidine at room temperature and a macromolecule containing chloride and methyl functional groups (PEG-Cl(2)-Me(2)) was obtained. Substitution of chloride functional groups of PEG-Cl(2)-Me(2) by hydroxyl functional groups led to a macromolecule containing methyl and hydroxyl functional groups (PEG-Me(2)-OH(4)). Hydroxyl functional groups of PEG-Me(2)-OH(4) were reacted with cyanuric chloride and PEG-Me(2)-Cl(8) was obtained.