Blood cultures were positive in only one patient. Mycobacterium tuberculosis accounted for 16/19 (84%) confirmed

cases, M. bovis bacille Calmette-Guerin for one, M. avium complex for one, and one was culture-negative. Histology results were available within 24 hours; TB was confirmed exclusively by bone marrow in two cases.

CONCLUSION: Bone marrow biopsy is a valuable diagnostic procedure in children with suspected disseminated selleckchem mycobacterial disease. Ideally, patients should be referred prior to treatment initiation.”
“OBJECTIVE: To deliver rapid isoniazid (INH) and rifampicin (RMP) drug susceptibility testing (DST) close to the patient, we designed a decentralisation process for the microscopic observation drug susceptibility (MODS) assay in Peru and evaluated its reliability.

METHODS: After 2 weeks of training, laboratory staff processed >= 120 consecutive sputum samples each in three regional laboratories. Samples were processed in parallel with MODS testing at an expert laboratory. Blinded paired results were independently analysed by the Instituto Nacional de Salud (INS) according to predetermined criteria: concordance for culture, DST against INH and RMP and diagnosis of multidrug-resistant tuberculosis (MDR-TB) >= 95%, McNemar’s P > 0.05,

kappa index (kappa) >= 0.75 and contamination 1-4%. Sensitivity and specificity for MDR-TB were calculated.

RESULTS: The accreditation process for Callao (126 samples, 79.4% smear-positive), Lima Sur (n Crenigacestat mouse AZD1775 = 130, 84%) and Arequipa (n = 126, 80%) took respectively 94, 97 and 173 days. Pre-determined criteria in all regional laboratories were above expected values. The sensitivity and specificity for detecting MDR-TB in regional laboratories were >95%, except for sensitivity in Lima Sur, which was 91.7%. Contamination was 1.0-2.3%. Mean delay to positive MODS results was 9.9-12.9 days.

CONCLUSION: Technology transfer of MODS was reliable, effective and fast, enabling the INS to accredit regional laboratories swiftly.”
“Two new glycoside compounds, named saffloquinoside C (1) and (-)-4-hydroxybenzoic acid-4-O-[6-O-(2-methylbutyryl)--D-glucopyranoside] (2),

were isolated from the florets of Carthamus tinctorius. Their structures were elucidated by detailed spectroscopic means including UV, IR, HR-ESI-MS, 1D and 2D NMR, and CD data. Compound 1 was a rare quinochalcone glycoside with six five-membered dioxaspirocycle.”
“SETTING: North Carolina, United States.

OBJECTIVE: To investigate the demographic and behavioral risk factors associated with death among tuberculosis (TB) patients in North Carolina.

DESIGN: Retrospective cohort of all TB patients reported in North Carolina, 1993-2003 (inclusive). A surveillance dataset based upon Report of Verified Case of Tuberculosis (RVCT) records was cross-linked with the National Death Index (NDI) to confirm date of death and capture additional deaths.

03 and P = .04, respectively). In conclusion, abnormal language area protein synthesis in developmentally delayed children may be related to pervasive symptoms.”
“Objective. The peripheral odontogenic fibroma (POdF) is a rare benign neoplasm of odontogenic origin with limited data on recurrence. The purpose of this study was to define the clinical and histopathologic spectrum of POdF and to investigate its recurrence rate and variables associated with its recurrence.

Study design. A total of 151 cases of POdF were Selleck PHA-848125 accepted for this study, which documented clinical, histopathologic, and follow-up data. Multivariate

stepwise logistic regression was used to investigate the association of categorical variables and recurrence.

Results. POdF should be considered a mixed odontogenic tumor because it is composed of active odontogenic epithelial and ectomesenchymal components. Of the 58 cases with follow-up,

29 recurred. Budding of the basal cell layer of the surface squamous epithelium was associated with higher recurrence (P = .0186); 27 cases with recurrence which exhibited this feature. The presence of calcification in direct apposition to epithelial rests was associated with lower recurrence (P = .0076); 13 cases that did not recur exhibited this feature.

Conclusions. POdF has a 50% recurrence rate. Budding of the surface epithelium and calcification in apposition to odontogenic epithelial

rests are histologic predictors of recurrence. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;110:357-363)”
“Study this website MEK pathway Design. A 5-year prospective cohort study of cervical spine instabilities in rheumatoid arthritis (RA).

Objective. To clarify the natural course of cervical instabilities in RA patients and to determine predictors for the prognosis of RA cervical spine.

Summary of Background Data. Although several previous studies investigating the natural history of RA cervical spine have been reported, few of them have described radiological predictive factors for the aggravation of these instabilities.

Methods. Two hundred sixty-seven outpatients with “”definite”" or “”classical”" RA initially assigned were prospectively followed for over 5 years. Radiographic cervical findings were classified into three representative instabilities: atlantoaxial subluxation (AAS), vertical subluxation (VS), and subaxial subluxation (SAS). The aggravations of these instabilities were identified in the cases with a decrease of at least 2 mm in the Ranawat value of VS, an increase of at least 1 mm in translation of SAS, or a new development of respective instabilities. RA stages and mutilating changes were assessed in the hand radiograms.

Results. Fifty-two point four percent of 267 patients, without any cervical instability at the beginning of follow-up, decreased to 29.

Four cases undertook the mass resection and repairing operation with postoperative lumbar drainage; at final, they had to receive shunt operation. Six cases underwent mass resection and Z-VAD-FMK molecular weight repairing operation with shunt surgery at one stage; they recovered smoothly. Our results suggest that the adult patients with huge meningoencephalocele have larger subarachnoid cavity. When they receive repairing operation, their subarachnoid cavity would be decreased in volume and cerebrospinal fluid (CSF) circulation could be disturbed. In order to maintain the balance of CSF production and absorption, the shunt operation should be given at the same stage.”
“Our

growing understanding of how cerebral cortical areas communicate with the cerebellum in primates has enriched our understanding of the data that cerebellar circuits can access, and the neocortical areas that cerebellar activity can influence. find more The cerebellum is part of some large-scale networks involving several parts of the neocortex including association areas in the frontal lobe and the posterior parietal cortex that are known for their contributions to higher cognitive function. Understanding their connections with the cerebellum informs the debates around the role of the cerebellum in higher cognitive functions because they provide mechanisms through which association areas and the cerebellum can influence each others’ operations. In recent years, evidence from connectional anatomy

and human neuroimaging have comprehensively overturned the view that the cerebellum contributes only to motor control. The aim

of this review is to examine our changing perspectives on the nature of Vorinostat chemical structure cortico-cerebellar anatomy and the ways in which it continues to shape our views on its contributions to function. The review considers the anatomical connectivity of the cerebellar cortex with frontal lobe areas and the posterior parietal cortex. It will first focus on the anatomical organisation of these circuits in non-human primates before discussing new findings about this system in the human brain. It has been suggested that in non-human primates “”although there is a modest input from medial prefrontal cortex, there is very little or none from the more lateral prefrontal areas”" [33]. This review discusses anatomical investigations that challenge this claim. It also attempts to dispel the misconception that prefrontal projections to the cerebellum are from areas concerned only with the kinematic control of eye movements. Finally, I argue that our revised understanding of anatomy compels us to reconsider conventional views of how these systems operate in the human brain.”
“Aim. Although the effect of adolescent pregnancy on perinatal mortality and morbidity is known, data on the neonatal hospitalization rate in these deliveries have not been reported. We aimed to assess the possible effects of adolescent pregnancies on the hospital outcomes of the newborns.

Methods.

1063/1.3260233]”
“The elevated risk of triggering a myocardial infarction by smoking cannabis is limited to the first 2 h after smoking.

To examine the possible role of cannabis in cardiac deaths.

From 3,193 coroners’ cases over 2 years, there were 13 cases where the clinical information was compatible with a primary cardiac cause of death. An inquest was held in three cases. Myocardial infarction was the primary cause of death in 54%. Other causes BMS-777607 in vivo were sudden adult death syndrome, sudden death in epilepsy, and poisoning by alcohol and diazepam. Cannabis was mentioned once only on a death

certificate, but not as a cause of death. Blood delta9-tetrahydrocannabinol-carboxylic acid was recorded in one case and in

no case was plasma tetrahydrocannabinol (THC) measured.

To attribute sudden cardiac death to cannabis, plasma THC should be measured in the toxicology β-Nicotinamide mw screen in coroners’ cases where urine cannabinoids are positive. A positive urine cannabinoids immunoassay alone is insufficient evidence in the linkage of acute cardiac death and cannabis.”
“Telomeres and telomerase are targets for anticancer drug development and specific inhibitors are currently under clinical investigation. However, it has been reported that standard cytotoxic agents can affect telomere length and telomerase activity suggesting that they also have of a role in drug resistance. In this study, telomere lengths and telomerase activity as well as drug efflux pump expression, glutathione (GSH) levels and polyadenosine-ribose polymerase (PARP) cleavage were assessed in a panel of human tumor cell lines made resistant to vindesine, gemcitabine and cisplatin. These included two lung cancer cell lines resistant to vindesine (LXFL 529L/Vind, LXFA 526L/Vind), a renal cancer cell line (RXF944L/Gem) and an ovarian cancer cell line Nutlin-3a chemical structure (AG6000) resistant to gemcitabine, and one resistant to cisplatin (ADDP). The resistant clones were compared to their parental lines and evaluated for cross resistance to other cytotoxic agents. Several drug specific

resistance patterns were found, and various complex patterns of cross resistance emerged from some cell lines, but these mechanisms of resistance could not be related to drug efflux pump expression, GSH levels or PARP cleavage. However, all displayed changes in telomerase activity and/or telomere length. Our studies present evidence that telomere maintenance should be taken into consideration in efforts not only to overcome drug resistance, but also to optimize the use of telomere-based therapeutics.”
“Magnetic transitions in single-crystal alpha-Fe2O3 (hematite) nanowires, grown by thermal oxidation of iron powder, have been studied in the range of 5-1023 K with a superconducting quantum interference device below room temperature and with a vibrating sample magnetometer at higher temperatures.

A target is placed behind a scattering QNZ clinical trial medium. The impulse responses between all array elements are measured and form a matrix. The core of the method is to separate the single scattered echo of the target from the multiple scattering background. This is possible because of a deterministic

coherence along the antidiagonals of the array response matrix, which is typical of single scattering. Once this operation is performed, target detection is achieved by applying the DORT method (French acronym for decomposition of the time reversal operator). Experimental results are presented in the case of wide-band ultrasonic waves around 3 MHz. A 125-element array is placed in front of a collection of randomly distributed steel rods (diameter of 0.8 mm). The slab thickness is three times the scattering mean free path. The target is a larger steel cylinder (diameter of 15 mm) that we try to detect and localize. The quality of detection is assessed theoretically based on random

matrix theory and is shown to be significantly better than what is obtained with classical imaging methods. Aside from multiple scattering, the technique is also shown to reduce the aberrations induced selleck kinase inhibitor by a heterogeneous layer. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3200962]“
“Cladophialophora boppii is a dematiaceous fungus, which has been reported only rarely to be the cause of cutaneous infection. Herein we describe a C boppii parenchymal and bronchial infection in a lung transplant recipient. We also illustrate the clinicoradiologic patterns and review possible treatment options for these difficult infections. J Heart Lung Transplant 2009;28:635-7. Copyright (C) 2009 by the International Society for Heart and Lung Transplantation.”
“Following SB273005 inhibitor the removal of a hydatiform mole in a 34-year-old, 14-week pregnant patient, thyrotoxicosis and respiratory

insufficiency attacks were twice unexpectedly repeated. The symptoms were resolved with the administration of plasmapheresis, antithyroid and beta-blocker drugs and non-invasive mechanical ventilation; however, she was again operated due to prolonged elevated beta-hCG.”
“We present the experimental and micromagnetic simulation studies of coherent suppression of picosecond magnetization precession in Ni81Fe19 (Permalloy) microstripes with widths of 5, 10, and 12 mu m and length of 100 mu m in the presence of multiple spin wave modes. The lateral confinement of the microstripes causes spin wave modes of frequencies adjacent to each other, and the local suppression of the modes was experimentally achieved with field pulses of slightly different durations but with same rise time and fall time. Micromagnetic simulations show that application of the pulse field causes a large angle (similar to 135 degrees) reorientation of the magnetization, followed by a precession.

The information source preferred was again personal verbal information (82%), significantly higher than all other information sources (p < 0.001). In decreasing order, patients preferred telephone consultation (48%), E-mail consultation (44%), website information (41%), and leaflets (33%). 51% expected their headache to be cured, 71 and 57% requested effective prevention and fast relief of the headache episodes. 80 and 75%, respectively expected reduction in frequency and intensity. A total of 64% expected information about self-management and 52% expected to receive education on their headaches. The study demonstrates that patients in specialized

headache centres prefer personal information, that expectations are

very high, and PLX3397 inhibitor that education and information are important. Providing the right information Selisistat and thus give patients realistic expectations might enhance compliance and improve outcome.”
“Objective Epidural steroid injections (ESI) are the most commonly performed pain procedures. Despite numerous studies, controversy continues to surround their effectiveness. The purpose of this study is to determine whether a standard, clinical local anesthetic injection can predict outcomes for ESI. Study Design In this multicenter study, 103 patients received two ESI 2 weeks apart. Prior to their first injection, subjects rated the pain intensity of a standardized subcutaneous (SQ) injection of lidocaine prior to the full dose. Numerical rating scale pain scores were correlated with leg and back pain relief, and functional improvement, through 3-month follow-up. Outcome Measures A composite successful outcome was predetermined to be a 2-point decrease in leg pain score, coupled with a positive global perceived effect. Results A small but significant relationship was found between SQ pain score and reduction in leg (r=0.21, 95% CI 0.38 to 0.04; P=0.03) and back pain (r=0.22, 95% CI 0.36 to 0.07; P=0.03). Subjects with a positive outcome at

1 month had a mean SQ pain score of 2.5 (SD 1.9) vs 4.1 (SD 2.7) in those with a negative outcome (P=0.04). Subjects with SQ pain scores <4/10 had lower leg and back pain scores than those with pain scores 4 at 1-month (mean 3.2, SD click here 2.6 vs 5.1, SD 2.7 for leg, P<0.01; mean 3.7, SD 2.6 vs 5.0, SD 3.0 for back, P=0.02) and 3-month (mean 3.8, SD 2.7 vs 5.2, SD 3.1 for leg, P=0.01; mean 4.0, SD 2.6 vs 4.9, SD 3.1 for back; P=0.14) follow-up. Conclusions The results of this study found a weak positive correlation between SQ pain scores and treatment results. Further research should consider whether pain perception in conjunction with other variables might prove to be a reliable predictor for ESI and other procedural outcomes.”
“Brain white matter hyperintensities are more prevalent in migraine patients than in the general population, but the pathogenesis and the risk factors of these hyperintensities are not fully elucidated.

SUB1C is invariably present and acts downstream of the enhancement of GA responsiveness during submergence. In this study, heterologous Vactosertib ectopic expression of rice SUB1A and SUB1C in Arabidopsis thaliana was used to explore conserved mechanisms of action associated with these genes using developmental,

physiological and molecular metrics. As in rice transgenic plants that ectopically express SUB1A-1, Arabidopsis transgenic plants that constitutively express SUB1A displayed GA insensitivity and abscisic acid hypersensitivity. Ectopic SUB1C expression had more limited effects on development, stress responses and the transcriptome. Observation of a delayed flowering phenotype in lines over-expressing SUB1A led to the finding that inhibition of floral initiation is a component of the quiescence survival BEZ235 order strategy in rice. Together, these analyses demonstrate conserved as well as specific roles for group VII ethylene response factors in integration of abiotic responses with development.”
“In our recent study, pH-sensitive polyethersulfone (PES) hollow fiber membranes were prepared by blending poly (acrylonitrile-co-acrylic acid) (PANAA), and the electroviscous effect had great effect on the water flux change. While the question remains: is the water flux change caused by the electroviscous effect for all the membranes with different pore sizes? Herein, pH-sensitive hollow

fiber membranes with different pore sizes were prepared. The pore size and the theoretic water flux were calculated through the ultrafiltration of polyethylene glycol (PEG) solution. Comparing the calculated fluxes and the experimental ones,

we found that the water flux change was mainly caused by the pore size change at the pH value larger than pKa, while that was caused VX-809 molecular weight by both the pore size change and the electroviscous effect when pH value was smaller than the pKa, and the pore size change was caused by the ionization of the -COOH in the copolymer. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 123: 2320-2329, 2012″
“In the present study, we investigated the protective effect of Withania somnifera, an indigenous medicinal herb used in ayurvedic traditional systems for more than 3000 years in India, on gentamicin (GEN)-induced nephrotoxicity. The root extract of three different doses of W. somnifera (viz., 250, 500, and 750 mg/kg) was administered orally to rats for 14 days before GEN treatment and thereafter concurrently with GEN (100 mg/kg) for 8 days. Nephrotoxicity was evident in GEN-treated rats by significant increase in kidney weight, urea, creatinine, urinary protein, and glucose, and significant reduction in body weights and potassium, which was histopathologically confirmed by tubular necrosis. In contrast W. somnifera (500 mg/kg) significantly reversed these changes as evidenced microscopically when compared to other two doses of W.

Abnormalities in mitochondria, proteasome and lysosome function, as well as oxidative stress cause cell death in Parkinson’s disease. Thus, we exposed neuroblastoma (SH-SY5Y) cells to EC(50) of toxins that mimic these cell death mechanisms (dopamine to induce oxidative stress; naphthazarin to inhibit lysosome function; proteasome inhibitor N-carbobenzyloxy-Ile-Glu(O-t-butyl)-Ala-leucinal (PSI) to inhibit the UPS (ubiquitin proteasome system) and rotenone to inhibit AC220 mitochondria function) in the presence of five compounds

previously chosen as neuroprotective agents, and assessed cell viability. Coenzyme Q10 (117 mu M) significantly protected against four toxins, dopamine: 16.3 +/- A 3.3%; naphthazarin: 10.8 +/- A 1.1%; PSI: 16.2 +/- A 2.9%; rotenone: 53.2 +/- A 4.2%; whereas caffeine (140 mu M), creatine (25 mM), nicotine (1 mu M) and deprenyl (10 mu M) provided protection against some, but not all toxins. Interestingly, coenzyme see more Q10 is the only compound out of the five that showed neuroprotective potential in clinical trials. Thus, there is a direct correlation between the success of disease modifying agents in the clinic and their ability to protect against multiple cell death mechanisms in this assay. We propose that exposure of SH-SY5Y cells to different toxins that recapitulate cell death mechanisms in Parkinson’s disease serves as a rapid and reliable

method to test neuroprotective agents that may succeed in clinical trials.”
“The high-temperature electrical conductivity and thermopower of several compounds in the In2O3(ZnO)(k) system (k=3, 5, 7, and 9) were measured, and the band structures of the k=1, 2, and 3 structures were predicted based on first-principles calculations. These phases exhibit highly dispersed conduction bands consistent with transparent JPH203 purchase conducting oxide behavior. Jonker plots (Seebeck coefficient versus natural logarithm of conductivity) were used to obtain the product of the density of states and mobility for these phases, which were related to the maximum achievable power factor (thermopower squared times conductivity) for each

phase by Ioffe analysis (maximum power factor versus Jonker plot intercept). With the exception of the k=9 phase, all other phases were found to have maximum predicted power factors comparable to other thermoelectric oxides if suitably doped. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3530733]“
“Apparent occupancy levels of proteins bound to DNA in vivo can now be routinely measured on a genomic scale. A challenge in relating these occupancy levels to assembly mechanisms that are defined with biochemically isolated components lies in the veracity of assumptions made regarding the in vivo system. Assumptions regarding behavior of molecules in vivo can neither be proven true nor false, and thus is necessarily subjective.

For MSOME, spermatozoa were analysed at x8400 magnification by inverted microscope equipped with Nomarski differential interference contrast optics, Uplan Apo x 100 oil/1.35 objective lens and variable zoom lens. By Tygerberg criteria, the semen underwent morphological evaluation as described in the literature.

Regression analysis demonstrated significant positive correlation between percentage of normal sperm forms by Tygerberg criteria and by MSOME (r = 0.83, P < 0.0001). However, the incidence of normal spermatozoa by Tygerberg criteria (9.4%) was significantly higher (P < 0.0001) than under MSOME (3.3%). Despite the highly positive correlation, MSOME is a much GSI-IX stricter criterion of sperm morphology classification, since it identifies vacuoles and chromatin abnormalities that are not evaluated with the same precision by the analysis of Tygerberg

criteria. MSOME should be included among the routine criteria for semen analysis. In addition, MSOME should be used for selection of spermatozoa for intracytoplasmic sperm injection based on the already published literature, as this is a good selection tool.”
“Recent reports discuss the altered bone homeostasis in cigarette smokers, being a risk factor for osteoporosis and negatively influencing fracture healing. Cigarette smoke is known to induce oxidative stress in GW2580 clinical trial the body via an increased production of reactive oxygen species (ROS). These increases in ROS are thought to damage the bone-forming osteoblasts. Naturally occurring polyphenols contained in green tea extract (GTE), e.g., catechins, are known to have anti-oxidative properties. Therefore, the aim of this study was to investigate whether GTE and especially catechins protect primary human osteoblasts from cigarette smoke-induced damage and to identify the underlying mechanisms.

Primary human osteoblasts were isolated from patients’ femur heads. Cigarette smoke medium (CSM) was obtained using a gas-washing bottle and

standardized by its optical density (OD320) at lambda = 320 nm. ROS formation was CYT387 ic50 measured using 2’7′dichlorofluorescein diacetate, and osteoblasts’ viability was detected by resazurin conversion.

Co-, pre-, and post-incubation with GTE and catechins significantly reduced ROS formation and thus improved the viability of CSM-treated osteoblasts. Besides GTE’s direct radical scavenging properties, pre-incubation with both GTE and catechins protected osteoblasts from CSM-induced damage. Inhibition of the anti-oxidative enzyme HO-1 significantly reduced the protective effect of GTE and catechins emphasizing the key role of this enzyme in GTE anti-oxidative effect.

Our data suggest possible beneficial effects on bone homeostasis, fracture healing, and bone mineral density following a GTE-rich diet or supplementation.

Patients and controls were divided into 2 groups: those receiving a breakfast of 500 kcal and 21 g protein and those receiving no breakfast. Serum ammonia concentrations and cognitive functions were studied (Mindstreams; NeuroTrax, Fresh Meadows, NY) before and 2 h after breakfast. A mixed model was used to analyze the data.

Results: At baseline, cirrhotic patients had significantly lower total scores and significantly lower subscores (P < 0.015 global cognitive score) in 4 of 7 cognitive categories, which is indicative of MHE. Patients with hyperammonemia (>85 mu g/dL) scored significantly lower for attention

than did patients with normal serum ammonia concentrations (P < 0.003). After 2 h, MHE patients and controls responded differently to breakfast consumption

with regard to attention and executive functions (P < 0.003 and P < 0.04, respectively). Selleck JQ1 Although patients’ scores improved after breakfast consumption, despite an increase in serum ammonia, healthy controls who continued to fast performed better.

Conclusions: Chronic hyperammonemia may negatively affect attention. Eating breakfast improves attention and executive functions of patients with MHE. Prolonged periods of starvation may be partly responsible for these changes. This trial was registered at clinicaltrials. gov as NCT01083446. Am J Clin Nutr 2010; 92: 137-40.”
“We Rigosertib purchase demonstrate optical control of the LO phonon-plasmon coupled (LOPC) modes in GaAs by using a femtosecond pump-pulse Selleckchem GW-572016 pair. The relaxation time of the plasmonlike LOPC mode significantly

depends on the separation time (Delta t) of the pump-pulse pair. Especially it is maximized when Delta t becomes simultaneously comparable to the half period of the longitudinal optical (LO) phonon oscillation and resonant to the 3/4 period of the plasmonlike LOPC oscillation. We attribute these observations to the modification of carrier-LO phonon scattering and ballistic motion of the plasmonlike LOPC mode. (C) 2011 American Institute of Physics. [doi:10.1063/1.3562188]“
“A novel kind of macromolecule, long-chain alkyl quaternary ammonium functionalized hyperbranched polyester (QHPE), was synthesized by the reaction of hyperbranched polyester Boltorn H30 (H30) and 2,3-epoxypropyl alkyl dimethyl ammonium chloride under alkaline conditions in dimethylformamide. After modification, the hydroxyl terminal group of H30 was converted into an ammonium functional group. A series of products was obtained with different lengths of an alkyl chain (C8, C12, C16, and C18) in the ammonium functional group. All of the products were characterized by Fourier transform infrared and NMR spectroscopy. The application of QHPEs as accelerators for the alkaline hydrolysis of poly(ethylene terephthalate) (PET) fabric was studied.