The actuarial postbiopsy graft survival varied by cluster (p = 0.002). CAN and CNI toxicity were common diagnoses in each cluster (and did not differentiate clusters). Similarly, C4d and presence of donor specific antibody were frequently observed across clusters. We conclude that for recipients with new-onset late graft dysfunction, cluster analysis of Banff scores distinguishes meaningful subgroups with differing outcomes.”
“P>Soil salinity affects selleck kinase inhibitor a large proportion of the land worldwide, forcing plants to evolve a number of mechanisms

to cope with salt stress. Cytokinin plays a role in the plant response to salt stress, but little is known about the mechanism by which cytokinin controls this process. We used a molecular genetics approach to examine the influence

of cytokinin on sodium accumulation and salt sensitivity in Arabidopsis thaliana. Cytokinin application was found to selleck increase sodium accumulation in the shoots of Arabidopsis, but had no significant affect on the sodium content in the roots. Consistent with this, altered sodium accumulation phenotypes were observed in mutants of each gene class of the cytokinin signal transduction pathway, including receptors, phospho-transfer proteins, and type-A and type-B response regulators. Expression of the gene encoding Arabidopsis high-affinity K+ transporter 1;1 (AtHKT1;1), a gene responsible for removing sodium ions from the root xylem, was repressed by cytokinin treatment, but showed significantly elevated expression in the cytokinin response double mutant arr1-3

arr12-1. Our data suggest that cytokinin, acting through the transcription factors ARR1 and ARR12, regulates sodium accumulation in the shoots by controlling the expression of AtHKT1;1 in the roots.”
“Identification of regulatory relationships between transcription factors (TFs) and their targets is a central problem in post-genomic biology. In this paper, we apply an approach based on the KPT-8602 support vector machine (SVM) and gene-expression data to predict the regulatory interactions in Arabidopsis. A set of 125 experimentally validated TF-target interactions and 750 negative regulatory gene pairs are collected as the training data. Their expression profiles data at 79 experimental conditions are fed to the SVM to perform the prediction. Through the jackknife cross-validation test, we find that the overall prediction accuracy of our approach achieves 88.68%. Our approach could help to widen the understanding of Arabidopsis gene regulatory scheme and may offer a cost-effective alternative to construct the gene regulatory network. (C) 2011 Elsevier Masson SAS. All rights reserved.

(C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 112: 1082-1087, 2009″
“The characteristics of advanced discharge modes were investigated through measurements of spatiotemporal infrared emission, discharge current, infrared intensity, and luminous efficacy in an ac plasma display panel with an auxiliary electrode located between scan and common electrodes. Pulse waveforms that included find more auxiliary pulses applied to the auxiliary electrode after every sustain pulse were used. The proposed advanced discharge modes are as follows: In mode 1, strong discharges are generated by the sustain pulses only, whereas strong discharges are generated

by the sustain pulses and a weak discharge is generated by the auxiliary pulse applied after the scan pulse in mode 2. In mode 3-1, strong discharges Tyrosine Kinase Inhibitor Library are generated by the sustain pulses and weak discharges are generated by the auxiliary pulses applied after the scan and common pulses, while all sustain and auxiliary pulses generate discharges having similar intensities in mode 3-2. Mode 1 and mode 2 are efficient modes; the luminous efficacy was improved in mode 1 owing to more homogeneous discharge due to the auxiliary electrode and a priming effect due to the auxiliary pulse. The luminous efficacy was also improved in mode

2, because of decreased power consumption induced by a decrease in wall charges and sustained or increased luminance due to priming particles. Mode 3-1 and mode 3-2 are inefficient modes; the luminous efficacy was reduced in mode 3-1 as a result of a decrease in the luminance due to insufficiently generated priming particles. The luminous efficacy was also reduced in mode 3-2, because of short-coplanar-gap discharges of the sustain pulses. It was found that advanced discharge modes were changed successively from mode 1 to mode 3-2 when sustain or auxiliary pulses of higher voltage were applied. The maximum luminous efficacy can be obtained in mode 1 at a low sustain pulse voltage and in mode 2 at mid and high sustain pulse voltages. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3176904]“
“The article

describes the preparation of cast copolymer sheets of methyl methacrylate with varying mole CX-6258 nmr fractions of N-(p-methoxyphenyl) itaconimide/ N-(2-methoxy-5-chlorophenyl) itaconimide/N-(3-methoxy-5-chlorophenyl) itaconimide monomers by bulk copolymerization using azobisisobutyronitrile as an initiator. The effect of incorporation of varying mole fractions of N-aryl-substituted itaconimides in poly(methyl methacrylate) (PMMA) backbone on the thermal, optical and physicomechanical properties of cast acrylic sheets were evaluated. The glass transition temperature and the thermal stability increased with increasing amounts of itaconimides in the polymer backbone. An increase in tensile strength, flexural strength, and storage modulus was also observed. The impact strength decreased marginally upon incorporation of imides into the polymer backbone.

Their structures were elucidated using spectroscopic methods (mainly 1-D and 2-D NMR). All the guttiferones were tested for their cytotoxicity

towards three human cancer cell AZD9291 datasheet lines, MCF-7, Hela, and NCI-H460. Among the tested compounds, guttiferone Q showed potent cytotoxicity, having IC(50) values in the range of 2.74-4.04 mu g/ml, against the investigated cells. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.”
“Acute alcohol challenge studies in rodents and naturalistic observations in drinking alcoholics suggest that alcohol stimulates the hypothalamic-pituitary-adrenal (HPA) system. The literature on respective studies in healthy volunteers is more inconsistent, suggesting differential alcohol effects depending on dosage, recent drinking history, family history of alcoholism and alcohol-induced side effects. These papers and the putative pharmacologic mechanisms underlying alcohol effects on the HPA system are reviewed here and compared with a new study, in which we investigated how secretion of adrenocorticotrophin (ACTH) and cortisol is affected by ingestion of 0.6g/kg ethanol in 33 young healthy

socially drinking males with a paternal history of alcoholism (PHP) versus PI3K inhibitor 30 family history negative (FHN) males. Alcohol and placebo were administered in a 2-day, double-blind, placebo controlled crossover design with randomized administration sequence. After administration of placebo, ACTH and cortisol decreased steadily over 130 minutes. In FHN subjects, secretion of both hormones was even more attenuated after alcohol, resulting in significantly lower levels compared with placebo. In PHP subjects, no alcohol effect on hormone secretion could be detected. The ratio of cortisol to ACTH secretion, each

buy G418 expressed as area under the secretion curve, was significantly increased by alcohol in FHN and PHP participants. These results argue against HPA stimulation being a mechanism that promotes the transition from moderate to dependent drinking. The fact that alcohol-induced HPA suppression was not detected in PHP males is consistent with the general concept that subjects at high risk for alcoholism exhibit less-pronounced alcohol effects.”
“The utilization of laser technology in conservative dentistry offers several advantages compared with traditional instruments, but one of the still unsolved problems is the difficulty in describing and explaining these advantages to patients. The aims of this study were to verify the efficacy of the way patients are informed and to evaluate their satisfaction with laser-assisted treatment.

Results:

Treatment with SFC plus Tio significantly decreased WA/BSA (P <

0.05), WA% (P < 0.01) and T/root BSA (P < 0.01), and increased Ai/BSA (P < 0.01), whereas treatment with Tio alone had no effect. The changes in WA/BSA and Ai/BSA were significantly correlated with increases in FEV(1) (r = 0.48, P < 0.05, and r = 0.36, P < 0.05, respectively). There were significant improvements in SGRQ scores after treatment with SFC plus Tio.

Conclusions:

Airway wall thickening and airway narrowing MK-0518 decreased after treatment with SFC plus Tio, and the changes in airway dimensions were proportional to the improvements in FEV(1). These results suggest that SFC plus Tio is more effective than Tio alone in the management of COPD patients.”
“Bilateral enlargement of both epididymes was observed in a 6-year-old German shepherd dog following a pre-scrotal urethrostomy. Testicular parenchyma Etomoxir inhibitor showed regular structure, and the spermatogenesis and the steroidogenic functions were not modified. However, macroscopic examination of the tail and the body of both epididymes exhibited multiple white and well-delimited foci. Histopathological study of the epididymes confirmed the development of granulomas associated with

extravasated spermatozoa. Urethrostomy caused a severe stenosis of the penile urethra, favouring the retention of urine at the urinary bladder. The retrograde pressure exerted by the distension of the urinary bladder could have allowed the urine to reach the prostatic urethra and the deferent ducts and, finally, the epididymes, causing irritation and rupture of the mucous layer of the epididymal duct, the consequent sperm

extravasation and the development of sperm granulomas. We speculate that the click here inadequate surgical resolution of the urethral calculi caused the bladder distension, the subsequent retrograde flow of urine and the development of the lesions.”
“OBJECTIVE: The aim of this study was to assess the IgE serum levels in juvenile systemic lupus erythematosus patients and to evaluate possible associations with clinical and laboratory features, disease activity and tissue damage.

METHODS: The IgE serum concentrations in 69 consecutive juvenile systemic lupus erythematosus patients were determined by nephelometry. IgG, IgM and IgA concentrations were measured by immunoturbidimetry. All patients were negative for intestinal parasites. Statistical analysis methods included the Mann-Whitney, chi-square and Fisher’s exact tests, as well as the Spearman rank correlation coefficient.

RESULTS: Increased IgE concentrations above 100 IU/mL were observed in 31/69 (45%) juvenile systemic lupus erythematosus patients. The mean IgE concentration was 442.0 +/- 163.4 IU/ml (range 3.5- 9936.0 IU/ml). Fifteen of the 69 patients had atopic disease, nine patients had severe sepsis and 56 patients presented with nephritis.

Ninety-eight patients returned the retest questionnaire. Data quality was also assessed. Assessment of psychometric properties included examination of data quality, construct validity, test-retest reliability and factor analysis.

The quality of data was good with no missing answers and a little floor effect. Exploratory factor analysis revealed a single-factor structure. Reliability expressed as intraclass correlation coefficient was 0.88 (95 % CI 0.84-0.92) for the

overall COMI score and was generally good for most of individual core items. The minimum detectable change (MDC95%) was 1.97.

This version of the COMI-neck is a valid and Stem Cell Compound Library cell assay reliable instrument, with good psychometric properties. It can be recommended for Polish-speaking patients.”
“Background: Little is known about the use of warfarin in hemodialysis (HD)

patients with atrial fibrillation (AF). We studied temporal trends of AF among older HD patients, and of warfarin use among those with AF.

Methods: We linked US Medicare and prescription claims from older patients undergoing HD in 2 Eastern US states. We established annual cohorts of prevalent HD patients; AF was ascertained CX-6258 molecular weight from >2 claims (>7 days apart) in the same year, with a diagnosis code indicating AF. Among those with AF, we defined current and past warfarin use. Demographic and clinical characteristics were also ascertained for each cohort. We used repeated-measures logistic regression to define the odds of AF and of current or past versus absence of warfarin use.

Results: Of 6,563 unique patients,

2,185 were determined to have AF. The prevalence of AF increased from 26% in 1998 to 32% in 2005. In 2005, current warfarin use was present in 24% of AF patients and past use in 25%; 51% had no evidence of any warfarin use. No significant trends in utilization were observed from 1998 through 2005. Patients aged >= 85 years and nonwhites Volasertib clinical trial were less likely to have received warfarin; most comorbidities were not associated with warfarin use except for patients with past pulmonary embolism or deep venous thrombosis who were more likely than those without such history.

Conclusion: While the prevalence of AF has been increasing among older HD patients, warfarin use was low and unchanged over time, perhaps reflecting the lack of evidence supporting its use.”
“Objective: The aim of the study was to identify factors associated with worse physical and emotional functioning of breast cancer survivors with upper extremity lymphedema.

Methods: 1250 sets of questionnaires consisting of WHO-DAS II, EORTC QLQ-C30, EORTC QLQ-BR23 and GHQ-30 were mailed to women who underwent a breast cancer surgery at the Lower Silesian Oncology Center in Poland between January 1998 and December 2005.

Results and conclusions: The response rate was 33.47%. 117 women were included into a lymphedema group and 211 into a group without this complication.

They were followed up clinically, biochemically (lipid profile), and ultrasonographically at 6 months and 1, 2, and 3 years after surgery. Postoperative prophylactic bile salt therapy (ursodiol) was not prescribed. Of the 40 patients, 38 completed the 3-year follow-up. They were divided HDAC inhibitors cancer into two groups: those who formed gallstones and those who did not. These groups were compared with

respect to gender, age, preoperative body mass index (BMI) and lipid profile results, and postoperative percentage of excess BMI lost (%EBL) and lipid profile results.

The overall postoperative incidence of CL was 28.9 % (11 out of 38), with a 15.7 % incidence of symptomatic CL (6 out of 38). Gender, age, preoperative BMI, postoperative %EBL, and preoperative and postoperative lipid profile results were not identified as predictive factors for CL after RYGBP.

There was a high incidence of CL after RYGBP, occurring primarily in the first

2 years postoperatively. There was no identified predictive factor for gallstone formation after RYGBP. Most patients who formed gallstones were symptomatic, some with potentially severe complications.”
“Objective: Antimicrobial resistance is one of the biggest problem in medicine at the beginning of the third millennium. Antibiotic resistance is frequently associated with significant morbidity, longer hospitalization, excess costs and mortality. Methods: In this work we discussed the role of clinical microbiology laboratory as an essential

part for an effective HIF inhibitor review infection control program, especially in management and treatment of “”difficult infections”". Results: At present time, laboratory personnel have a broad range of new technologies that they can use to support and enhance the efforts of the infection control staff. In addition a network of established experts in the determination of antimicrobial breakpoints and in antimicrobial susceptibility testing has been constituted in Europe under the auspices of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the European Centre for Disease Prevention and Control (ECDC). Conclusion: Qualified personnel and new strategies to overcome drug resistance can contribute to solve the microbial infections problems.”
“A previous MLN8237 molecular weight study has demonstrated that symptoms suggestive of dumping syndrome appear after a provocation test early after laparoscopic sleeve gastrectomy (LSG) in 45 % of patients, and these are mainly related to early dumping. The aim of this study is to evaluate the evolution of dumping symptoms during the first postoperative year.

Twenty-five non-diabetic morbidly obese patients (6 male, 19 female) were evaluated with an oral glucose tolerance test (OGTT) preoperatively, at 6 weeks and at 6 months postoperatively. In addition, 12 of them repeated the OGTT at 12 months after LSG.

4 x 10(6) J/(m(3) K) at high temperature, in agreement with experiments, and provides insight into the low-temperature range (<150 K), where data are unavailable. (C) 2011 American Institute of Physics. [doi:

10.1063/1.3639279]“
“Influenza A H1N1 2009 led to 189 deaths during the Australian pandemic. Community-acquired respiratory viruses not only can cause prolonged allograft dysfunction in lung transplant recipients but have also been linked to bronchiolitis obliterans syndrome (BOS). We report the impact of the 2009 H1N1 pandemic on Australian lung transplant recipients. An observational study of confirmed H1N1 cases was conducted across five Australian lung transplant programs during the pandemic. An electronic database collected patient learn more demographics, clinical presentation, management and outcomes up to a year follow-up. Twenty-four H1N1 cases (mean age 43 +/- 14 years, eight females) P5091 research buy were identified, incidence of 3%. Illness severity varied from upper respiratory tract symptoms only in 29% to lung allograft dysfunction (>= 10% decline FEV1) in 75% to death in 5 (21%) cases (pre-existing BOS grade 3, n = 4). Treatment with oseltamivir occurred in all but one case confirmed after death, reduced immunosuppression, n = 1, augmented corticosteroid therapy, n = 16, and mechanical/noninvasive ventilation, n = 4. There was BOS grade decline within a year in six cases (32%). In conclusion,

Australian lung transplant recipients were variably affected by the H1N1 pandemic mirroring the broader community with significant morbidity and mortality.

https://www.selleckchem.com/products/ink128.html After initial recovery, a considerable proportion of survivors have demonstrated BOS progression.”
“Background: In human malaria, the naturally-acquired immune response can result in either the elimination of the parasite or a persistent response mediated by cytokines that leads to immunopathology. The cytokines are responsible for all the symptoms, pathological alterations and the outcome of the infection depends on the reciprocal regulation of the pro and anti-inflammatory cytokines. IL-10 and IFN-gamma are able to mediate this process and their production can be affected by single nucleotide polymorphisms (SNPs) on gene of these cytokines. In this study, the relationship between cytokine IL-10/IFN-gamma levels, parasitaemia, and their gene polymorphisms was examined and the participation of pro-inflammatory and regulatory balance during a natural immune response in Plasmodium vivax-infected individuals was observed.

Methods: The serum levels of the cytokines IL-4, IL-12, IFN-gamma and IL-10 from 132 patients were evaluated by indirect enzyme-linked immunosorbent assays (ELISA). The polymorphism at position +874 of the IFN-gamma gene was identified by allele-specific polymerase chain reaction (ASO-PCR) method, and the polymorphism at position -1082 of the IL-10 gene was analysed by PCR-RFLP (PCR-Restriction Fragment Length Polymorphism).

Double-staining immunohistochemistry (DIHC) of CD44 and CD24 was performed on 30 normal breast tissues, 30 breast fibroadenomas (FA), 60 breast invasive ductal carcinomas (IDC), and 3 breast cancer cell lines (MCF-7, MDA-MB-468, and MDA-MB-231). In the normal breast tissues and FAs, three phenotypes were observed including CD44<SU++</SU/CD24<SU++</SU, CD44<SU++</SU/CD24<SU–</SU,

GKT137831 cost and CD44<SU–</SU/CD24<SU–</SU cells. In the IDCs, CD44<SU–</SU/CD24<SU++</SU cells were detected, in addition to the three aforementioned phenotypes. The strong positive rate (++++++, incidence > 60%) of CD44<SU++</SU/CD24<SU–</SU was significantly increased PCI-34051 from normal breast tissue, FAs to IDCs (0.0%->-> 6.7%->-> 21.7%). However, the CD44<SU++</SU/CD24<SU–</SU cells didn”t correlate with ages of patients, lymph node metastasis, tumor size, molecular subtypes, and the expression of ER, PR, HER-2, PS2, Bcl-2, nm23. The proportion of CD44<SU++</SU/CD24<SU–</SU cells in MCF-7, MDA-MB-468, and MDA-MB-231 was about 1, 5, and 80%, respectively. The results indicate that the CD44<SU++</SU/CD24<SU–</SU cells are transit progenitors

and have no association with the molecular subtypes and clinicopathological parameters in the IDCs.</.”
“Background: To evaluate the effect of lifestyle intervention in conjunction with rosiglitazone or placebo therapy on left ventricular (LV) mass, using cardiovascular magnetic resonance (CMR) in the metabolic syndrome.

Methods: The present study was a pre-specified substudy of a double-blind randomized controlled trial evaluating the effect of lifestyle intervention in conjunction with rosiglitazone or placebo therapy on carotid artery atherosclerosis in the metabolic syndrome. From this original study population, 10 subjects from the placebo group and 10 from the rosiglitazone group were randomly selected. At baseline and follow-up

(52 weeks), clinical and laboratory measurements were assessed and a CMR-examination was performed to evaluate LV mass indexed for body surface area (LV mass-I). Subsequently, the effect of therapy (rosiglitazone vs. placebo) and clinical and laboratory variables Cell Cycle inhibitor on LV mass-I was evaluated.

Results: In both groups, body mass index, waist circumference, systolic and diastolic blood pressure significantly decreased during follow-up. Interestingly, LV mass-I significantly decreased in the placebo group (48.9 +/- 5.3 g/m(2) vs. 44.3 +/- 5.6 g/m(2), p < 0.001) indicating reverse remodeling, whereas LV mass-I remained unchanged in the rosiglitazone group (54.7 +/- 9.9 g/m(2) vs. 53.7 +/- 9.2 g/m(2), p = 0.3). After correction for systolic and diastolic blood pressure and triglyceride, the kind of therapy (rosiglitazone vs.

The diabetic TB patient AS1842856 group contained more males (72%) and smokers (45.5%) compared to the nondiabetic group (58.3% and 33.5%, resp.). Approximately 74% of diabetic patients were Mycobacterium sputum positive compared to only 51% of nondiabetic patients. Diabetic patients were also more likely to develop pulmonary TB (87%) compared to nondiabetic TB patients (59%). Diabetic TB patients had a higher mortality rate (7.5%) compared to the TB only and DM only groups (1 and 2%, resp.). The duration of TB symptoms was longer in nondiabetic TB patients compared to diabetic TB patients (4.5 versus 2.6 months, resp.). Diabetes antedated TB by a mean time of 4 years. Conclusions. We found

a higher number of sputum-smear-positive cases and pulmonary

TB cases as well as a greater number of males and higher mortality rate in diabetic patients compared to nondiabetic patients.”
“Fossa navicularis magna is a congenital anomaly representing persistent dehiscence of the basiocciput. This tract from the nasopharynx to the brain is common and carries a potential risk for infection. Nevertheless reports on such dissemination are very rare. We present a child with brain infection via a fossa navicularis magna, the first description to our knowledge, and review the literature on this anomaly. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“The aims of this paper were to evaluate the relationship between chronic pain and global quality of life (GQOL) and to explore the effect of possible confounders, ABT-263 chemical structure mediators, and moderators such as selected demographic variables, chronic illnesses, stress-related

symptoms, fatigue, and subjective health of the relationship between chronic pain and GQOL.

We used a cross-sectional design, including 1,893 respondents from a population of 4,000 of Norwegian citizens, aged 19-81 years, who were randomly drawn from the National Register by Statistics Norway in November 2000 (48.5%). Pain duration of more than 3 months was categorized as having chronic pain. The Quality of Life Scale, the Fatigue Severity Scale, and the Posttraumatic Stress Scale were used as our main dependent and independent variables, respectively. A series of multiple 3-MA chemical structure regression analyses (GLM in SPSS) were applied using GQOL as the dependent variable, entering subsets of independent variables in a theoretically predefined sequence.

In the total model, there was no significant relationship between chronic pain and GQOL. The model explained 39% of the variance in GQOL. For direct effect sizes, stress-related symptoms were related most strongly to GQOL, followed by subjective health, fatigue, chronic illnesses, and selected demographic variables.

These findings support the assumption of a complex and indirect relationship between chronic pain and GQOL.”
“Pancreatic beta-cells, which secrete the hormone insulin, are the key arbiters of glucose homeostasis.

On the contrary, the magnetic anisotropy constant, K-eff, shows a nonmonotonic behavior. The K-eff decreases from its bulk value, shows a minimum near phi similar to 30 nm and

displays an important increase for smaller sizes. We analyzed the size dependence of K-eff in terms of the magnetocrystalline and surface contributions, and we fitted the K-eff size evolution on the basis of a phenomenological model taking into account the magnetically ordered core and the surface contribution. (C) 2010 American Institute of Physics. [doi:10.1063/1.3506535]“
“Poly(ether ether ketone) (PEEK) composites reinforced by short carbon fibers (SCFs) and nanoscale zirconium dioxide (ZrO(2)) particles were prepared by twin-screw extrusion compounding and subsequently injection molding. The effects of SCFs and ZrO(2) nanoparticles on the mechanical properties and LDC000067 in vivo wear behavior of PEEK composites with water lubrication check details were investigated. The mechanical properties of the composites were dramatically enhanced by the incorporation of SCFs. The addition of nano-ZrO(2) also promoted efficient improvements in the stiffness and hardness but degraded the impact strength. The compounding of the two fillers remarkably improved the wear resistance of the composites under aqueous conditions and especially under high pressures. The excellent wear resistance of the PEEK/carbon fiber (CF)/ZrO(2) composites

under aqueous conditions was revealed to be due to a synergy effect between the ZrO(2) nanoparticles and CFs. The SCFs carried the majority of the load during a sliding process and prevented severe wear of the matrix. The incorporation of nano-ZrO(2) efficiently inhibited CF failure by reducing the stress concentration on the CF interface and the shear stress between two sliding surfaces via a positive rolling AZD2014 supplier effect of the nanoparticles. Furthermore, a linear correlation was found between

the wear rate and some mechanical properties of the composites. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 1711-1720, 2011″
“Objective. The aim of this study was to investigate the feasibility of autogenous coronoid process pedicled on temporal muscle grafts (ACPTMG) for reconstruction of the mandible condyle, and to compare the differences in clinical effects with autogenous free coronoid process grafts (AFCPG) in patients with temporomandibular joint (TMJ) ankylosis.

Study design. From 2003 to 2005, 48 patients who were diagnosed with uni- or bilateral TMJ ankylosis were randomly divided into 2 groups: group A( 24 cases, 28 joints) and group B( 24 cases, 30 joints). All patients underwent operations for resection of condyle and surrounding bony masses and simultaneous recreation of the glenoid fossa, which was followed with, for group A, condylar reconstruction using ACPTMG and, for group B, AFCPG, as well as interposition of temporal muscle myofascial flaps or native articular disc.